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The Food and Drug Administration, FDA, has approved the drug Vivitrol for the treatment of opioid dependence in accordance with a news release by them on 10-12-2010.

Using two separate drugs to shed weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people that go through it you ought to err on the side of caution and let the FDA do its job and demand some investigation be done so that the public knows the side effects and dangers of the medications before we take them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on his or her medications.

Researchers found that participants investing in this drug for a year, lost excess weight within 4 weeks and have kept the load off during the entire 56 weeks from the study. Contrave is a combination of the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which can be made up of multiple active ingredient, which might make them far better and safer.

Combo-pilling may be the newest fad or also the newest ahead under scrutiny and so it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular is the fact that at the time of right now there aren't any long term prescription slimming capsules that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA.

Seizures really are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug can also raise hypertension and pulse rate, and shouldn't be used in individuals with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must 't be used in patients with uncontrolled high blood pressure levels, and also by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients having a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

"There were no signs and symptoms of depression or suicidal thoughts in trial participants," said Fujioka.